Continuum and Non-continuum Modelling of Nanofluidics

Recent development in nanoand biotechnology has opened a new field of microand nanofluidics. Many MEMS (micro-electro-mechanical-systems) and NEMS ( nano-electromechanical-systems ) are based on the fluid motion. Additionally, the analysis of biological samples, drug design and nanomedicine are connected to nanoliter fluid flow. The challenge for understanding such small systems lies in the difficulty to perform experiments as well as in developing theory and simulations methods. Modeling of nanoscale fluid flow is especially complicated, because in contrary to macroscale, general equation are not well defined. Hence, even if the numerical method is well suited for solution of considered problem, the theory needs always be extensively validated with experiments. In this brief summary, the focus will be paid to the numerical models suitable for such systems.